Ask Us Anything About Hormones with Dr. Carrie Jones, May 10, 2019 | Mastering Nutrition #67


welcome back everybody this is dr. Chris
Master John of Chris master John PhD Khan and you’re listening to episode 67
of master nutrition ask us anything about hormones featuring my guest dr.
Carrie Jones which took place on May 10th 2019 as an ask us anything for
members of the cmj master pass this is a stirring nutrition with Chris master job
take control of your health Astor the science and apply it like a pro are you
ready in this episode we have dr. Carrie Jones
as a guest Carrie Jones is a naturopathic physician with a master’s
in public health having over 12 years in the field of functional integrative
medicine she served as adjunct faculty for the national university of natural
medicine teaching courses in gynecology and advanced endocrinology she has been
the medical director for two large integrative clinics in Portland Oregon
and is currently the medical director for precision analytical the creators of
the Dutch test she frequently lectures teaches and writes on adrenal thyroid
and sex hormones you can find her at dr. Carrie Jones calm and if you have
Instagram I would highly suggest following her on Instagram her handle is
dr. kerry jones with dr. spelled dr period so the dr period CA RR ie jo and
es dr. kerry jones she puts out a lot of good content educating people on
hormonal health over on instagram there so some of the questions that come up in
this ask us anything which came to take dr. jones and me I gave her most of the
limelight but I pop in with my own opinions fairly frequently some
questions that came up were what time of day is best to take t4 or t3 questions
about using pregnenolone to manage perimenopausal symptoms such as insomnia
30 year-old male with normal total testosterone but high sex
hormone-binding globulin and low free testosterone suffering from sexual
dysfunction low libido trouble packing on lean muscle poor mood and low
motivation what should he do what to do when even small amounts of iodine cause
fatigue a woman who had a surgical procedure to prevent cervical cancer
lost sexual sensation libido and the ability to have a cervical orgasm and
began experiencing nerve pain in her pelvic muscles and legs whenever putting
pressure on the cervix she asks can sex damage the healing
nerves and Canberra gesture own or vitamin e help and are they safe and of
course what else can she do a man who had been on testosterone replacement
therapy for five years and then stopped it for five years now has low
testosterone and low libido but good muscle strength should he go
back on the testosterone another person asks what nutrients are needed to make
hormones another asks what causes waking up too early and why does it seem to
correlate with depression what causes night sweats in men nutrition for breast
cancer prevention why would a woman stop obviating during her cycle or stop
having a cycle altogether can anything be done to reverse hypothyroidism other
than taking thyroid meds should Hashimoto’s be treated with iodine
restriction what kinds of hormonal problems if any could be caused by a
ketogenic diet is there an optimal number of meals per day to take
advantage of the positive effects that insulin has on thyroid function and
should a 69 year old female avoid taking testosterone if she’s starting to lose
her hair get the answers to these questions and discussions surrounding
them by listening on for the full episode first a word from my sponsors this episode is brought to you by ample
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modern world has left out alrights few people are popping in now
can it can everyone hear me good is my volume good if if not type something in
the chat and then let’s see is is Carrie here yet okay Carrie just came in cool
all right hi dr. Jones hi there how are you good
yeah so so I gave everyone your intro or your bio in the description and then
when we released a recording I’ll put it in again and so I’ll just assume
everyone knows who you are but real quickly I asked dr. Carrie Jones to come
on and talk about hormones because she is the medical director for precision
analytical which makes the Dutch hormone test which is a very complete look at
metabolites of hormones that gives you incredible insight into what’s actually
going on and like why something might be higher low instead of just whether is
something’s higher low and so she studies this stuff all the time I
thought it’d be cool to have her field some questions and she has given follow
her on Instagram you’re on Instagram make sure you follow her on Instagram
because she talks about hormones over there all the time so come on yeah
thanks for having me you like my I feel like I’m like my gaming headset here
it’s awesome actually I should probably have does anyone hear any echo or
feedback for me I’m gonna put my earphones in just usually I use my Apple
you know my little white apple things and then the right had the right side
just busted it stopped working so I had to resort to my like formal headset I’m
so sad yeah okay cool my volume hasn’t changed does it okay cool
all right so for those of you who have not been in one of these things before
the way it’s gonna work is please do not use the chat for almost everything so if
you want to type a question type it in the Q&A section
if you want to respond to a question that is being that was entered into the
Q&A section do so by replying to the QA and actually I just realized that now I
need to think I need to adjust the settings let me see oh here it is okay
so I just change the settings so that you can comment on other people’s
questions so if you want to jump in on a conversation for a question that is
coming through the Q&A the proper place to do that is to reply there but one
thing that will use the chat for is if someone wants to come on the screen and
ask the question live they can raise their hand and I’ll call on them and let
you in and then the only way that you can jump in on someone else’s question
is to use the chat so chat will be used exclusively for that and I guess so all
more or less act as the moderator and go through the questions have enough to get
to everyone so I’ll just mostly handle them in order and then carry all field
the questions to you first most of the time and then if I want to I feel like I
have something to say I’ll jump in on it sound good I hope you have something to
say alright so the first question is and I’m gonna I if there are multiple people
posting as anonymous I’m sorry but I’m gonna treat anonymous as a person
otherwise I can’t make sure that everyone gets in gets their questions
and so I’m just gonna rotate through like one question each person and come
back okay so anonymous says can you give any guidance on what time of day it is
best to take t4 and or t3 Carrie do you have any thoughts on that
oh that’s a good really good question and it actually depends if you’re taking
immediate-release t4 or t3 especially or a sustained release because t4 has a
much longer half-life which is why we traditionally say to take it in the
morning since it helps with energy metabolism and all those things although
I do know some people choose to take their tea for at night before bed but t3
has a very short half-life and so what I’m finding is of some practitioners are
now doing what’s called a sustained release t3 so they take your t3 and it
helps sustain longer throughout the day or they will take their t3 twice they’ll
take it in the morning and then it’ll sort of take it again in the
mid-afternoon now if you’re taking a combination t4 t3 such as armor or
nature–the roit you can’t get the sustained part so that I dunno some
people who will take their armor or their nature thyroid in the morning and
then they will take an additional dose of t3 in the early afternoon like an
extra you know whatever it is two and a half five micrograms of t3 I think the
old-school way to get the time release was to nibble on a set amount tablet all
day literally I don’t know anything about this but I know that some people
you think that circadian rhythm is an important thing in timing yeah yeah I be
hearing that more and more just because of the clock gene and things like that
which is why I am hearing it’s not formally being prescribed this way but
when you break read chat boards and stuff like this people are actually
switching their thyroid to the night time to see if they get a different
response than how they feel in the day and I’m which i think is pretty
interesting and by and I mean their teeth it’s 34 not 33 I mean I don’t know
that I would take t3 before bed probably why are you right up but I have had some
folks switch their t4 today evening time just for then you know and they sleep
their t4 because it has a long half-life it’s already in their system and you
know been working while they’ve been asleep but traditional is you take it in
the day because that’s when the thyroid is active and doing its things and
that’s when you want it active okay cool that’s what you want the
activity of the hormone I should say hmm oh yeah Mindy Cabrera says I’m looking
for an informed opinion on the use of pregnenolone
to manage perimenopausal symptoms particularly insomnia which I get early
in my cycle and mid cycle it seems to help but I don’t feel
and using it anything else would be better anything else that that would be
better for GnRH induce insomnia well so here’s the thing about pregnant alone so
oral or sublingual so if you’ve got drops or little tablets you suck on
pregnant alone and progesterone when they go through first pass you swallow
them and then go through first pass they turn into other metabolites one is
called alo alo which is short for alo pregnenolone
alo binds to your GABA receptors in your brain now lo can cross the blood-brain
barrier binds to gabba gabba of course is your calming relaxing everything’s
gonna be okay hormones so pregnant alone or all pregnant alone and oral
progesterone actually work on the anxiety and on the insomnia from a gaba
point of view if it’s not oral do you know like is there normally
endogenous alone it’s a neuro steroid so your brain makes it and then break down
a progesterone can turn into ello and that can cross the blood-brain barrier
so you make you make it yourself in the brain but is women with especially if
you are headed in a perimenopause you’re not ovulating you’re not getting that
robust progesterone peak in the luteal phase it falls it close to your period
and now in the early part of your follicular phase then it you’re hurting
because you’ve missed out you didn’t get any of that sustained to progesterone
release that turned into ello and insomnia is really common around the
cycle and really common in perimenopause right I would say other than weight gain
I would say insomnia is probably the other big symptom I hear for
perimenopause that’s Carrie do you find that the in song is different between
people who are are aren’t on HRT yes sort of so if it’s strictly a hormone
issue if she says I’ve never had insomnia
I turned 45 but I got insomnia and oh by the way I’m also having irregular
periods and hot flashes and night sweats and all this stuff
I find that going on HRT generally resolves their insomnia if they’ve had
insomnia their whole life and oh by the way
they’re having hormonal issues as well or they’re perimenopausal going on HRT
may or may not help their insomnia because their insomnia may be induced by
of course other things cortisol blood sugar parasites
you know thyroid hypothyroidism you know hyperthyroidism and so then I find that
it’s much more systemic as opposed to just the women who say to me I turned 40
and can’t sleep or I turn 45 and I can’t sleep I’m like oh Harry menopause yeah
I’m curious mainly because it seems like in some women estrogen can be a cause of
insomnia so we had talked about one of my clients a while back who had estrogen
through the roof reasons and inseong it was a major thing that she was dealing
with I believe it I can believe it it’s like Goldilocks right like problem
problem but if you think about it to the highest region pushes tryptophan down
the criterion pathway get away from serotonin and melatonin so if you have
excessively high amounts of estrogen you’re going to likely make a little bit
less serotonin and melatonin and that can really affect your mood and then
it’ll affect your melatonin so your sleep yeah I was I was looking at a
paper on this recently and it looks like even though estrogen stimulates the
beginning of the kind of random pathway it stimulates the end of it a lot more
and so you can in addition not getting melatonin and serotonin you can get
quinol innate which can have cytotoxic or an excitatory neurotransmitter
building up and might have you have you put any thought into why that happens
because my thought right now is that is that it’s bit that that pathway is how
you make niacin from tryptophan and so I think that it’s basically the body
trying to make sure that the baby has enough niacin because chronic estrogen
exposure would occur during pregnancy brand and so one thing that I’ve when I
was doing my nice and research one thing that I found is that
women women seem to need more total niacin than men but they seem to be
better at making niacin from protein and what’s really interesting is that the
studies that were done that were used to make the RDA they weren’t comparisons of
men and women but two of the studies were madam two studies were in women and
the standard deviations meaning how much variation there was person to person in
how much niacin that they needed to normalize what they were looking at was
way bigger in men than it was in women and so one of the interesting things is
that it seems like and that is not this is not a strong conclusion but it’s a
it’s a it’s one worth talking about it seems like in men the ability to make
niacin from tryptophan is not regulated at all and it’s largely because if you
have too much tryptophan you need to get rid of it down that pathway and if your
ability to completely burn it for energy is topped off then quinol innate which
is neurotoxic will build up unless you convert it to niacin same with Kiner
neck right is anthe Roenick yeah well yeah everything that goes into
that like once you start going down that pathway you can build well yeah like if
you had a backup in that so kind of mannequins in thir and they are spilling
loft from higher parts of the pathway right that’s true if you have a block if
you have block in one of those parts and then if you have too much tryptophan
coming in they will build up right but if the block is not in those parts and
tryptophan goes down what it’s ultimately doing is it’s gonna be quite
burn for energy or it’s gonna go into quinol innate which is neurotoxic and
then into Indonesia and so in men and Majan that most of that pathways working
fine so you’re not getting buildup and gentler nating kinda ready if you get
down to completely burn the trip in front for energy and suddenly your
capacity to do that is locked up then at the very end of the pathways where you
have the quinol in E which is a potential neurotoxic risk it’s not the
Quinlan is poisonous it’s like glutamate like too much is right
and so and so niacin there is a making niacin for penile any is a way of making
sure that you don’t have neuro toxic levels of quinol innate building up so
it’s like a safety valve but but estrogen dramatically increases this
pathway and it increases the steps at the end that generate quinol any even
more than it increases the beginning of the pathway and as a result women have
much better ability on average than men to make niacin tryptophan but also they
seem to have a much more consistent ability in other words in many there’s
no regulation to it at all and so one man versus another man is really really
random whereas for women there’s variation but
it’s it’s in a much tighter range and that that variation is like probably if
you accounted for their estrogen levels probably now that would really narrow
the range down yeah absolutely really really really tightly regulated
by estrogen but but you know if your estrogen levels are really really high
and they’re consistently high and you’re not pregnant and you’re not using the
niacin for the baby and and you’re just exceeding the capacity to deal with that
coil in aid it seems like that’s the condition where you have where you where
you have the potential for that quintal any building up of estrogen that’s gonna
do dirty nasty things in the brain that it should be doing well and think about
the men to who are on who over aromatize I like or regulated testosterone life by
unregulated I mean um they’re just on testosterone
you know they’re just their doctor just ran into Stas terone just gave them
testosterone maybe it’s an injection it’s high dose here you go and all of a
sudden they’re like I feel like I felt good initially and now I feel whereas I
brain fog right I’m Moody I have this breast development what’s going on it’s
like well you’re just aromatized it all the estrogen and then if you have that
same pathway right yeah it’s a really great point in fact in one of these AMAs
a couple months ago when the first ones I did there was a
man who was asking why his b6 deficiency markers were so high and appendix
deficiency markers in the urine are the things we’re talking about right here
that’s black pathway yeah and I was asking him a few different questions
maybe reading too much protein this and that and then I mentioned something
about estrogen regulating it and he said oh by the way my estrogen is high and I
was like oh wow you know obviously I was inappropriately excluding that because
of the sex issue but yeah estrogen it’s not a not a just a female thing yeah for
sure yeah and then that whole cycle just keeps going round and round the one
marker there’s an tyranny which is a b6 dependent it’ll complex with insulin and
then they’ll make somebody have higher glucose right now they’re on the track
to developing insulin resistance and diabetes which further increases
estrogen especially in men and and then now you’re back on the same circle hmm
all right let’s go to Brendan Hanigan Brendan Hanigan is a 30 year old male
with high SHBG and low free testosterone total testosterone is normal 700 and
anna grams per deciliter higher but shbg ranges from 50 to 80 animals per liter
as a result free testosterone sits at the bottom of the range and sometimes
below it symptoms of poor testosterone status sexual dysfunction low libido
trouble building muscle mass without gaining a lot of fat low mood and
motivation background this is a background hypothyroidism that’s
currently well-managed the treat t4 and t3 no major weight
issues no sign of metabolic dysfunction and liver problems very low progesterone
high estrogen due to another case I yesterday and then due to progesterone
very low progesterone and high estrogen to progesterone ratio but absolute
estradiol levels are below range okay not in other cases at them and when will
prolactin DHEA never stage etc very low blood lipids TC total cholesterol around
100 to 140 for low Wow things that didn’t work
over-the-counter supplements to lower SHBG and increased free teeth were on
zinc various herbs like tongkat Ali etc and even a course of sir moorland an
adaptable gh secretin raising total filled 160-170 through cholesterol
supplementation looking for ideas what am I missing shbg is like the bane of my existence I
have no idea how to get SHBG down once it’s up and boy I sure talk to
practitioners about this all the time to figure that out I would agree that
supplements that for shbg it’s very hit-or-miss tongkat being one of them
DHEA being the other what’s the UH there’s two other ones Nettles
stinging nettles Oh a novena oats there’s like very mild very weak
research about lowering SHBG with nettles and then what’s Avena again it’s
like hit or miss so how do you get that a SHBG down well also remember STD binds
estrogen as well although he said his estrogens low so it’s not his shbg is
not going up because of a low absolute estradiol hmm low progesterone gives men
the same symptoms as low testosterone I don’t actually worry that that much
about progesterone because as the other things improve generally progesterone
improves as well generally yeah this so I’m curious how an increase in body fat
might affect this because they say okay so no major weight issues no sign of
metabolic dysfunction and liver problems um so I don’t know like it’s it seems to
me logically that a high SHBG is a bad thing and that seems supported by his
symptoms but if you look at the literature high SHBG seems like shbg
goes down with an increase in liver fat and insulin and and it seems and it
seems like a high SHBG is correlated with a lower disease risk for a variety
of things and so I think sometimes it might be counterintuitive but some
like maybe you need to wait a little bit more sometimes as in is an issue there
even though that’s that’s not a good answer if the person is not underweight
but um I’ve heard from some other I’m not an expert in this at all but I have
heard from some other practitioners mycotoxin will raise SHBG mycotoxin does
and what was the other one that does but I have not done any research into that
I’ve just had a few mycotoxin experts say see it all the time when we address
their mycotoxin their shbg goes back to normal like well that would make sense
right all your binding globulin sar gonna go up yeah bind and protects or
try to protect so you may Branden want to look into other things
viruses epstein-barr cytomegalovirus you know mycotoxin just things like that run
some inflammatory markers see what’s up and just see if you’re missing you’re
looking at the hormones but maybe you’ve run a lot of great stuff but maybe it’s
just the next layer down and the onion yeah I think it’s worth noting that his
cholesterol still isn’t very high that’s not good 100 to 140 yeah I mean he got
it so he says he used cholesterol supplementation to get it up to 160 to
170 dinos everyone whose family have low cholesterol is it just him yeah Brendan
if you’re able to comment on that um that would be an interesting question to
answer whether whether your family members have those issues or have the
cholesterol issue specifically I mean so my thought is and you know when I was a
vegan my cholesterol was 106 my total cholesterol but I was also like
borderline psychotic when I was a vegan and so I don’t think it was a good thing
but my even even on a high animal fat diet my cholesterol is around 160 or so
and in fact although it might be higher now I haven’t checked it in a while go
dad and grandpa have low total cholesterol too but not as extreme yeah hmm so I mean I kind of I don’t
think you should completely exclude that you might want to raise your cholesterol
higher than that I mean I know I know 160 and 170 would be looked at is really
really good from a you know from a cardiovascular person’s perspective like
your cardiologist doesn’t tell you you need it higher but um boy you know
cholesterol is is a precursor for the sex hormones and is going to be and is
going to be a factor in your body’s perception of how much abundance you
have and the fact that you needed cholesterol supplements to bring it up
to 160 to 170 makes me think that you that you’re the general state of
cholesterol in your body is is very very low by default and it’s still pretty low
and I you know I don’t know like what one 170 should be okay but I think given
the specific problems that you’re looking at pushing it up to 200 and
seeing if you feel any better is should be like one of the tools in the kit this
my plates it’s interesting that some of his hormones are low and some are high
like his total testosterone is high or in range I’m apologizing so he can make
testosterone right he’s the testicular ability to pull in cholesterol and make
it but his progesterone and estrogen aren’t absolutely high so those two are
less free is low but we know that’s bound up so well we don’t know what the
cholesterol content of his liver is boy but the liver lipids yeah I mean
obviously don’t want fatty liver but but there might be a threshold where like
the cholesterol content in the liver and the triglyceride content in the liver
are influencing the SHBG expression so my thought is yeah it’s it clearly it’s
not like the limiting precursor to the production of sex hormones but it might
be the thing it’s just like no one’s gonna give them a liver biopsy it’s a it’s a reasonable thought that
they might be influencing SHBG expression so yeah I mean neither of us
have good answers but all right thanks Brendan okay Eric
hush FAC says always mild fatigue reaction to even 100 micrograms of
iodine despite low thyroid peroxidase and TPA what’s TPA antibodies do all
right PPO and T I’ll let you read some oh I thought it was TG thyroid globulin
maybe that’s one de body and 24-hour urinary iodine is 53 micro grams which
is moderately deficient so okay so he he doesn’t look like he has pirate itis he
looks deficient in iodine small doses of iodine are giving him fatigue any
thoughts yes well one thought is a big one so
remember iodine belongs to the halogen family and other
halogens can bind onto your the T or tyrosine um so I have had this before
where a patients would take iodine and the iodine will push off you know the
fluoride and the chloride and the bromide off of the tyrosine and then
they get so it binds on and now you have with essentially kind of a detox
reaction so people will say I get headaches i broken out in rashes I’m
really tired because the how other halogens have come off the tyrosine and
are now floating around your system and so whenever I don’t actually I am I
believe in iodine I’m I’m not quite sure I fully
not I’m not sold yet on iodine testing there I feel like there’s so many rules
of thoughts but if I use iodine and I warn people of that of the detox you’re
not you’re not sure how valuable a 24-hour urinary iodine is I don’t use it
I don’t if I’m gonna spend money on a patient it’s not normally on a 24 hour
my my perception has been that the 24-hour urinary iodine is a good marker
of what you’ve been eating in the last day or so and if you you
could be I think where would be valuable is um if you don’t know the ion of
content of your diet which is almost guaranteed that you have no idea how
much iodine you’re eating because like it depends like if you’re if most your
iodine is coming from kelp you probably have a reasonably good idea of how much
iodine you’re getting but on a diet where most of your iodine is coming from
land foods then you have absolutely no idea because well you can get a general
idea like if you’re living in in like the an iodine deficient Belt in Illinois
and everything that you eat comes from the local farmers market you probably
have low iodine intake but like a potato from one part of the United States can
have a hundred times as much iodine as a potato from another part of the United
States so I think if you eat very consistently if you eat the same thing
every day at 24 1 24 hour iodine is probably a pretty good reflection of
diet and content of your diet and if for most people probably 3 or 4 24-hour
urinary iodine’s spread out across in a way that would capture a representative
sample of what they’re usually eating would probably give you a pretty good
idea of the intake it just it doesn’t really tell you your status though
because you know what’s your exposure to the other halogens and and things like
that but so I yeah but you’re probably right it’s it’s probably not the top
priority and spending money unless you unless you have reasons to think your
issue is iodine related and in this case he’s got fatigue reactions iodine so
it’s I guess it’s interesting what that is urinary iodine looks like he needs
more and I mean isn’t real high right so he doesn’t have iodine toxicity know
right exactly exactly so we know have you found in those cases where people
say or work people report these detox reactions iodine what have you found a
solution to this is this is you just take keep taking the iodine powerfully
yeah and do like you know sweating and binders and
things like that do another normal stuff you would do for a herxheimer type
reaction but it can take why did you wait it’s like what’s all the normal
things you do for her chain reaction so obviously like lots of water exercise
you know binders so like fibre and charcoal or zeolite or whatever you’re
doing to like bind this stuff up in your clay you know those supplements with
that sort of stuff in it saunas are really good sweating dry skin
brushing to try to help move it through your body while staying on the iodine
you want the iodine to bind to the tyrosine and not the halogen to rebind
because you stopped taking it so it’s just going to rebind rebind to your
tyrosine and I’ve seen it take you know a cup to a couple weeks depending how
halogen toxic that you are in fact I had a bus driver as a patient who drank
eight diet no eight mountain Dew’s a day because every she had a her shift she
had for long you know going this way and then for coming back to the station was
the consistency of her day and with every long drive she did she drank him
out do so eight Mountain Dews day so her first of all just to get her off
Mountain Dew was you know a struggle and then and then her reaction was we worked
with thyroid and thyroid was a big thing for her detox iodine lifestyle her
reaction was a long time because she’d been drinking eight Mountain Dews for a
long time I was trying to get the bromine out of her system yep yeah
that’s a lot of Mountain Dew yes yeah yeah I always avoided it because of the
rumor on the street when I was a teenager was that it would make your
testicles shrink I always had the most caffeine I never Mountain Dew I never
gotten a mountain Dew ever I don’t even like to taste but my friends are always
who drank it were always like what has the most caffeine content not as much as
some of the things out there now oh my gosh yeah this is yours
when I was much younger all right thank you Eric for your question Gary Krieger
says would a seasonally low vitamin D level he lives in northern Michigan
combined with a high calcium intake 1500 mm by he must need milligrams 500
milligrams from supplements so a thousand a 1500 from diet 500 milligrams
from supplements would this increase the risk for soft tissue calcification in
vitamin A k2 magnesium levels were adequate for with the calcium simply be
excreted due to low vitamin D levels I’ll take the first I was like okay so
the seasonally low vitamin D level despite high calcium with that increase
with I’m not Gary if you can follow up I’m not sure if you’re asking would the
low vitamin D level increase the soft tissue calcification or with the cows
the high calcium do so you could answer right away yeah okay so so the end of
this question is would the calcium simply be excreted due to the low
vitamin D levels so your vitamin D level being low the first thing that’s gonna
do and the major thing that’s gonna do is it’s going to lower your calcium
absorption and so you would have more calcium excreted in the feces as a
result of not absorbing it if your vitamin D level is low however a high
enough calcium intake is going to more than compensate for that so it depends
how low it is I mean if you if you live in northern Michigan and you’re not
supplementing with vitamin D in the winter but you’re getting out your
outdoors a lot your vitamin D is probably not going like rickets level
loan it’s you know it’s probably dipping a bit and account a calcium intake of
two thousand milligrams is so high that you’re probably absorbing at least
enough calcium and the vitamin D being low the so that me
then once the calcium is in your system one of the problems with low vitamin D
is that it’s gonna take more calcium to suppress your parathyroid hormone and
you want your parathyroid hormone maximally suppressed for the sake of
your bone health but again a high calcium intake like that may well
completely compensate for that now the soft tissue calcification is going to be
driven by on the one side so you could view it as like a calcium in calcium
calcium and calcium mount you could view it as a pro calcification anti
calcification equation and so the calcium phosphate product which is the
the concentration of calcium your blood times the concentration of phosphorus in
your blood is gonna be the Crowe calcification side that equation and the
protective factors that are like the proteins that are made by AD and
activated by k2 the magnesium and a couple other things are going to be
defending the soft tissues against calcification and so the the low vitamin
D is probably not gonna change your calcium phosphate product that much the
calcium intake I mean 2,000 milligrams I think is pushing the safe limit of
calcium it’s it’s not necessarily harmful but it’s it’s calcium doesn’t
have a huge window I think one thousand and two thousand milligrams is probably
the safe window for calcium and so yeah it depends how low the vitamin D levels
are so like if it’s going down to twenty or twenty five nanograms per milliliter
it’s probably not gonna interfere that much with the ability of the other
things to defend you against soft tissue calcification but below that it might
and if it’s dipping from like sixty to forty nanograms per milliliter it’s
probably just that you know vitamin D has a u-shaped curve with calcification
so you don’t want to be deficient but when you get up into 5060 nanograms from
leader you’re you’re not asking the question of whether you need more
vitamin D to protect against soft tissue calcification you’re asking whether you
might have too much so yeah that’s if it’s going down to 30 no issue at all if
it’s going down to like 20 or 25 you might you might want to take us you
might want to measure your vitamin D levels your parathyroid hormone levels
and use a little bit of extra vitamin D if you need to to normalize those levels
you know bring 2500hd up to 30 ish or a little higher bring PTH to 30 ish or
lower and yeah that’s that’s my thought do you
have anything to add Carrie no maybe I just have to I’m I’m
copying and pasting these questions into a list and because I was answering that
one I forgot to do it – all right thank you Gary for your question
Jillian Harkey says I had a leap procedure
le EP 5.5 months ago at really weeks post-op and since I’ve lost Carrie
what’s what is a le EP procedure that where they remove the surface part of
the cervix usually it’s for lesions so precancerous lesions or for yeah cancer
itself Thanks I had I had a procedure five point five months ago at three
weeks post-op and sends a lost sexual sensation and libido can no longer
barely have cervical orgasms and experience nerve pain in my pelvic
muscles and legs if I put pressure on the cervix good progesterone in vitamin
E oil applied directly to the cervix help reverse any possible post-surgical
fibrosis if progesterone is progesterone safe to take to see if it helps with
libido and then she follows up also could sucks and orgasms I can still out
a clitoral vaginal orgasm if I really concentrate have damaged healing nerves
could sex and orgasms have damaged healing nerves I guess she’s asking for
too much clitoral and vaginal orgasms damage the nerves in that context or
could my own bodily environment and probably not let me just finish those
two sentences left or could my own bodily environment have been a perfect
storm for poor healing I don’t know what is due to nerve damage or just due to
hormones I don’t know what is happening to me any thoughts so yeah with the leap
procedures so like I was saying is basically it’s kind of like a hot knife
through butter so they taste they cut away a portion of the cervix and in a
sometimes it’s a little portion and sometimes they do what they call like a
full like they slide it right across the face of the cervix and if you remember
so those of you who maybe never seen a cervix it’s shaped like a doughnut like
literally it’s like your cervix is this tiny little pink doughnut and has a hole
in the middle and the hole is you know leads up into your uterus and so for a
lot of women there’s a lot of nerve sensation there so it does to greatly
affect orgasms other women don’t have it there’s probably women listening who
were like mine’s not sensitive at all is that normal yep totally normal
every woman is different so for her though in particular she did have a lot
of nerve sensation there on the cervix so first of all progesterone is a
hormone never just take a hormone because you heard it’s good and want to
try it definitely you know at least talk with your practitioner get your
progesterone levels checked in in the second half of your cycle the luteal
phase and see and if then yes you need progesterone then yes girl try it
absolutely you can’t directly apply the cervix you can you can do progesterone
bagent lee yes no it’s not you would have to have it compounded or because
you the topical creams on the market are not meant to be vaginal they’re meant to
be on the outside of the skin not the inside so be very careful of that you
want it compounded specifically for vaginal application there are a few
over-the-counter or there’s one I don’t actually I don’t think they’re
over-the-counter there’s a company called bez wacken and theirs is made in
coconut oil and in vitamin E oil so it is safe for vaginal purposes but you
still have to be a practitioner to to get access to it but yes then you can
use progesterone and you can absolutely use vitamin E capsules you can break the
capsule and insert it up there vaginally to try to help no I will say the other
thing that I found really really helpful for things like that acupuncture believe
it or not pelvic abdominal type acupuncture is
really helpful and there’s specific like abdominal pelvic massage so just like
you have physical therapy for your shoulder or your knee there’s their
physical therapists who do who are specially trained in certain kind of
massages to focus in and around the uterus and the you know that it’s
all it’s usually all external and so there’s two to kind of bigger groups one
is called our Vigo touch than a are Vigo so you can look on their website our
Vigo massage see find the massage therapists and physical therapists who
were trained the other is the mercy a therapy which is M er CI ER so Tasaday
mercy ER but it’s more CA exactly so it helps with like nerves and congestion
and and muscular support in and around sort of that whole pelvic area but yeah
you can absolutely it and keep in mind you just had surgery so and it takes a
really long time for nerves to grow back I think they grow like the research
shows they grow back with like a millimeter a month and so if you you
just had that those nerves scraped away or the end scraped off it’s gonna take
months to to reconcile that it’s it’s nerves are hopeful not fast growing but
it is definitely possible yep yeah absolutely yeah he’s a good one Thank
You Gillian for your question and ER Strom says I have been on testosterone
replacement therapy for five years and stopped five years ago my total T is
very low between 100 in the a.m. and 45 in the PM I have been off I’ve been off
doesn’t put the units that’s very low if it’s what I’m familiar with nice or not
I’ve been off from tears now and there’s a few if you’re if you’re replying could
you put the units in for the testosterone I’ve been off for two years
now how long should I wait it out before his results are nanograms per milliliter
apparently because his free tea is 1.4 nanograms per milliliter good gracious
I’ve been off for two years now how long should I wait it out before giving up
and going back I feel good but there are risks with prolonged low tea my fruity
is 1.4 nanograms per milliliter and 50 but have good muscles strengthen us and
I’m not putting on weight but libido is pretty low well first of
all I would want to find out why you aren’t making testosterone so I would
definitely have your practitioner run an LH on you luteinizing hormone the total
is nanograms per deciliter okay so men have hormone just like women do comes
from the brain and it’s what stimulates the testes to make testosterone so
Anders if you have low LH that I know it’s a brain problem not necessarily a
testicular problem and if your LH is normal this is LH and FSH are good how
about prolactin how about prolactin Anders thyroid
thyroid heavy metals like lead what concentrates in the testicular
tissue I’ll just throw in my my stuff here so I am so MK for the is a form of
vitamin k2 that in the testicles through it increases the gene expression
involved in testosterone synthesis and osteocalcin is a vitamin k2 dependent
protein that is kept in the bone and released during bone resorption that
stimulates testosterone production in the male testes so you can actually
measure under carboxylated osteocalcin in the blood through either quest origin
I think it’s Genova that has the under carboxylated version but that would be
worthwhile and I put vitamin K in one of the list of things that you could look
into is prolactin his good thyroid is good hmmm
definitely check vitamin K vitamin K heavy metals yeah on the list
I was gonna say his question was how long do i wait till I throw in the towel
yeah you know how old is he does Oh 55 I missed that part
okay okay I’m gonna if you just got your testosterone checked in you says it’s
vitamin K is good well dang trying to think of other big
reasons for suppressed um doctors how was your sleep and insulin then how is
your insulin sleeps like a rock he feels good has he tried kilometer HCG said he tried
any of those to try to get his own to stick your their production up their
vendors have you tried any them dangerous stuff he says give you answers
if you did a trial of clomid and your own testosterone prediction did not go
up then you know you’ve got right you’re they’re just your latex cells are not
making testosterone but if you do climate and your testosterone does go up
it’s a lot more encouraging that you have the ability still mmm so you don’t
do it long-term we just use it as trial to see if your
latex cells are actually yea able to produce testosterone anymore so you can
use you can use it short-term for diagnostic purposes that makes sense to
me he says mk2 eight six six works um I’m
not sure if that is I don’t know what that is either let me google it
it’s like a pedia that Ostrom hasta Ryan it’s a selective androgen receptor
module right right right okay okay and he said that works somewhat yeah I mean
that doesn’t really answer anything about why the testosterone is low right
so is his testosterone is low and he compensates for that by using a
selective androgen receptor agonist right just replacing that’s not doing
anything to the testosterone or providing any answers to why it’s low
okay so we got try clone it and see if it goes up is a test worth doing as a
short-term trial to take any answers but if it does it’s more couraging it means
that your cells are still like you know I kind of wonder and ER says have you
had you done testosterone tests before that were higher or do we have any
reason to think that they’ve always been this low I mean I am a little bit
curious if I know there’s health risks of having low testosterone like but
there’s got to be normal variations that um I don’t know some it would be
interesting to know if this was age-related or if or if he had low
baseline so it’d be 3:40 before he went on TRT minutes his total of course yeah
it will must be but he’s but now his total is 45 I thought it was 145 no no
it’s a hundred in the in the morning in 45 and night Heights so he had he had a
lot higher before he went on TRT so it looks like he’s got long-term
suppression or you know that was ten years ago
so or it’s he’s 55 now he was 45 before so might be significant – yeah
any history of steroid use and has used others other circulates opioids I’m
seeing that more and more no no ok you have any thoughts on his actual question
which is how long should he wait it out before going and giving nothing going
back oh don’t wait I would go get a climate challenge now because then I
would say it’s the testicular cells or function it or not yeah I mean if the
question is how long should he wait the profit waiting is probably not gonna
give you any more answers and it was giving you for the last five years right
and waiting probably isn’t gonna raise your testosterone I mean if you have one
measurement that it’s 100 in the morning and 45 the night you don’t really know
if it’s increasing like maybe six months ago it was 50 so if you wanted to wait
what I would do is to do some follow-up testing to see if there’s a if it’s
actually changing over time but I mean if it’s been flattened out for five
years I don’t think it’s going anywhere but if it’s been going up 10 nanograms
per million grams per deciliter every three months for the last five years
then then you probably could wait it out but without knowing that there’s no data
indicating that waiting is a is a good strategy here it sounds like so I would
agree all right Thank You Anders I have already okay li w says any suggestions
on supplements to assist with delayed onset muscle soreness
I’ve tried l looming and haven’t noticed much improvement I’ll jump in here and
you can add if I mean how much to say but my thoughts are I mean my thoughts
are usually usually Don’s is a recovery issue and I don’t know it
like maybe acid buffering like beta-alanine or bicarbonate but probably
probably just get used to your exercise and rest more unless it’s a unusually
repeating thing and what do you think Kerry that’s definitely not my area of
expertise so I’ll come back on May 25th Saturday when we have asked us anything
about sports nutrition where I have some three guys who are better than me at
sports nutrition and that’ll be the time to answer that all right yes thank you a
question needs Anita Morgan says how does the body make
hormones and what nutrients and foods to do this question that’s a I think that’s
a very general question this question in the lab because a doctor was fighting
with one of my doctors as to what nutrient raises estrogen and the doctor
was was just knew she was new to hormones and she’d been in a different
field of medicine and she was like what hormone can i or what nutrient can I
give you a test raise estrogen and it made me realize just how much people
don’t realize how female hormones are made since she’s females I’ll start with
female so and most the time when people say how our hormones made they think
they’re thinking estrogen and progesterone when I get out of that
question right from woman so women ladies you have two ovaries you should
have two ovaries you’re born with you a braised dairy and they’re surrounded by
follicles and on the follicles are cells and inside the follicle is the egg
that’s gonna eventually pop out so you have initially the start of your month
you have two types of cells you have what’s called fika cells and that makes
your testosterone and you have your granulosa cells and that’s what makes
sure your estradiol your e to right there and your ovary so your
testosterone actually aromatize ah’s into your estrogen and your granulosa
cells and then you ovulate so once you kick out an egg the granulosa and the
theca cells turn into lutein cells or your corpus
it’s the luteal phase of your of your cycle the second half and those cells
make progesterone and and your progesterone goes up and then if you’re
not pregnant your progesterone comes down if you’re pregnant then your
progesterone stays up until your plus and then gradually starts to come down
and your placenta makes progesterone it takes over so but hormones first and
foremost as Chris said earlier come those hormones come from cholesterol so
cholesterol is the backbone to all of your hormones they’re called your
steroid hormones and cholesterol is is pulled into the cell and then it’s
pulled into the mitochondria and it goes through a series of steps to eventually
make the hormone that you’re looking for testosterone which I mentioned estrogen
and then of course it makes progesterone and so that’s how it’s made in a cycling
woman so then I get asked well where’s where the rest of it is the rest of it
made so testosterone has also made ladies in your adrenal glands you make
about 25-ish percent in your adrenal glands and there you do make some in
your fat tissue as well from another hormone called and roast netted I own
and then as you go through menopause and now your ovaries the follicles and your
ovaries are gone to do a Breezer closed for business then you make the most of
your estrogen out of your fat tissue ladies you can take your testosterone
made from your adrenal glands and your fat tissue and convert it into what’s
called a stirone or e1 and then e1 can become the potent e ii version so you
still make you still eat out a little estrogen and menopause and then
progesterone is actually sort of made out of the adrenal glands we hardly make
any progesterone like like near zero as we go in in menopause
but the adrenal glands will release some progesterone when it’s making like
cortisol or you know some of the other hormones in menopause but it’s it’s like
micro tiny amounts so that’s ladies how you make estrogen progesterone and
testosterone which is usually what people are asking when they say how do I
mean where’s it made from now as far as nutrients go like I said it cholesterol
is the backbone to all of your hormones so much like the gentle
who said earlier his cost was quite low it can impact the way and the amount of
hormones that you make the lower your cholesterol is the tougher time you can
have to make hormones but the more cholesterol you make doesn’t necessarily
mean you’re gonna have mass amounts of hormones it’s a very tightly controlled
system but as far as like nutrients go really it’s a signaling that we’re
working with since nutrients are helpful but like it’s not like we say like oh
this nutrient makes estrogen there’s no nutrients that I can you can give to
create estrogen but what we can do is we can help the brain communicate with the
ovary and we did to make to get the estrogen production happening we can do
all the cellular health like the healthy fats and you know the fish oils and and
you know choline and things that make your did your cell membranes really
healthy and so that they can light so they can make hormone and hormone can
you know come out into your system and on top of that your hormones are
transported through your blood so if you are a smoker if you have diabetes if you
just if you are not very active you don’t like to exercise you’d be very
stagnant then your hormones are also gonna have a tough time circulating
around because it’s the your circulatory system is not very good it’s not very
healthy so your hormone from your brain will have a tough time getting down to
the hormone from your ovary or out of your ovary over to your your skin or
your heart or your lungs or wherever it needs to go and so that’s kind of like
my quick a quick snapshot for women where are those hormones made now
obviously there are other hormones thyroid hormone cortisol brain hormones
but usually women mean estrogen and progesterone when they’re asking me that so I’ll just throw out I have not done a
comprehensive deep dive into every nutrient that’s needed to make hormones
but um but first there was a very interesting study done I think was in
the 1990s I forget but it was done in boys who are
not undergoing puberty and they compared vitamin A and iron to testosterone
treatment and to a couple other androgen treatments and the kids that got vitamin
A and iron like the vitamin A and iron was just as potent and actually acted
twice as fast induced puberty as they as the testosterone and mother indigence
did and you know you can be pretty sure that those kids were deficient in
vitamin A and iron though and the amount that they gave listen wasn’t a lot boy
hormones dip in zinc deficiency – and the I mentioned before that
vitamin K can act as a signaling compound for synthesizing hormones and
vitamin D and calcium can can affect the signaling to produce sex hormones – I
think if we went through and looked at all of the enzymes involved at least
iron would be involved in some of those cofactor for some of those enzymes we
would probably find other things – I don’t know what they all are yeah I
think there’s a lot of nutrients where you know for one like whatever is gonna
work is really gonna be highly dependent on what missing link right sue someone
zinc deficient then probably if their hormones are messed up thing that’s
gonna work is you’re gonna replace the zinc right right not everyone is ink
deficient and there’s a lot of people who have hormone problems that aren’t
fundamentally about micronutrients for some people it’s in enough food for some
people it’s a fad for some people to have too much body fat stress much food
there’s stress and so many things that probably if you were deficient in almost
any nutrient enough there’s gonna be something messed up about your hormone
it’s more of a it’s more of an individual thing where you have to look
for what’s actually gone wrong in that person it’s not a direct
it’s not like if you give this and if you give vitamin C you’re going to
create cortisol out of it or if you it’s not it’s not how those hormones salutely
well you might increase the levels of something crazy there is the effect of
vitamin C on hormones is not very well studied but but there is but there there
is a study showing I forget the exact findings or study out there showing that
vitamin C supplementation increases sexual intercourse you realize all your
listeners are gonna go out and be like vitamin C please well you you may be may
be a statistician my question I don’t know but well so so like vitamin C is
needed for so one of the things in the brain that controls the production of
all of these hormones we’ve been talking about more is is the production of neuro
peptides that have elf what is it called alpha pet I forgot the name of it it’s
like alpha peptidoglycan something I don’t know but there’s two enzymes that
are dependent on one’s depend on vitamin C and copper and the other is
structurally depend on zinc the vitamin C and copper are redox cofactors and
they’re needed to activate half of the neuro peptides and among the neuro
peptides that are activated or all of the hypothalamic releasing hormones so
we usually call them hormones but those are neural peptides and so if you didn’t
have enough vitamin C and copper more copper in in that you know to make the
nerve peptides that could be a reason why you’d have low T Rho G n re
or any of the releasing hormones and so your thyroid hormones your sex hormones
and your adrenal hormones could all wind up getting kinked because of that and so
I guess the question is how deficient do you need to be for those also oxytocin
which is needed for the you have pair-bonding response to physical
intimacy is is one of those neuropeptides that needs to be activated
in that way so it’s a reasonable hypothesis that vitamin c status could
impact the production of thyroid hormone sex hormones and renal hormones and so
maybe that yeah an oxytocin come on that can play a role and how often you have
sex with your spouse Tosun guys yeah so I but you know but it
still comes back to the thing like yeah I feel like if biological complexity is
sort of like an onion you know you can talk about one thing like that but then
you peel back that layer and you say well okay like how does the copper in
vitamin C get into the brain or like what made the enzyme that use the
vitamin C and copper to do that you just start tracing back the layer and the
layer eventually you’re gonna see that all of the vitamins all of the minerals
the fat the protein and the carbohydrate and how much you ate are all going to be
things that can influence the hormone levels an answer that that’s that is
that a question that is that general is it potentially has an answer that just
says everything right and then the only way to make that more specific is the
start narrow narrowing down the case by saying okay and in this person who has
this context with this specific problem and then right at that point you might
be able to say well it’s probably a nutrient it’s probably not a nutrient
while I sleep it’s probably stress it’s probably whatever it might be so a very general question you know very
thoroughly let’s the anonymous says why is early morning waking a characteristic
symptom of depression and what other conditions and balances of early waking
as a symptom I know this answer oh you know the answer I do I might but when
you have the early morning waking when you wake up in the morning they just are
there it’s called the cortisol awakening response we shortened it to the car
cortisol awakening response and it’s a nun it’s historically a non-stress
driven natural rise in cortisol researchers aren’t 100% sure other than
maybe for survival so when you wake up in the morning you want to be alert you
need to be conscious you need to be ready to go just in case there’s you
know bad things around you that any and you’ve been asleep but we do know the
cortisol awaking in response it happens in about the third first 30 to 60
minutes of your day literally from the time your eyes open your cortisol should
shoot up to a point and then gradually come down for the rest of the day
now with depression so I it’s heavily studied if you have an elevated or
excessive cortisol awakened in response meaning you go higher you your spike is
higher and more dramatic than the average bear then your risk for morning
depression is much higher and the reason for that is we’ve already touched upon
with estrogen and the serotonin versus Chi narrating pathway because high
excessive glucocorticoids or cortisol can also up regulate the pathway away
from serotonin and down towards kynurenine and so if you wake up with
excessive amounts of cortisol for whatever reason you’re stressed out
you’re anticipating your day you wake up and pain you wake up with inflammation
you you know something startled you awake like you’re your kid is throwing
up it can it can increase your risk for morning depression because it pushes
that all that excessive cortisol pushes your tryptophan away
from serotonin and down towards Kiner and then as Chris said if you are going
down the kynurenine pathway and you already have issues with that you can
make that that quinol innate which is a which is a neurotoxin as well so now
you’ve lost serotonin a more Quinn Olynyk acid which is neurotoxin and now
you’ve got potentially this double whammy if not a single whammy against
you so that’s one of the big when they do the research on to prep morning
depression it’s one of the big things they’re studying is that it’s the
excessiveness of your cortisol awakening response in the morning are you a hyper
person are you normal or you flatlined do you go down and then if you go down
that’s a whole different thing that does all sorts of other stuff mmm were you
gonna say something different no I didn’t know that and I and I probably I
would just throw I mean I’ll throw out a couple other
yeah things that I think could theoretically be an issue so so I mean
in addition to the glucocorticoids influencing where tryptophan goes I have
a I have a sneaking suspicion and I don’t I don’t have good data supporting
this but it just makes sense to me and it seems to make sense with some
people’s anecdotal stories I think that part of the so the the half-life of
melatonin is really short and you have to you have to produce it all night long
basically and I think that and you eat my meal right not gut its contacts and
so it it can definitely be a limiting factor in onset some insomnia not have
melatonin and one of the things that can limit that is getting tryptophan into
the brain and tryptophan gets into the brain mainly as a result of the ratio
between tryptophan and competing amino acids in the blood
the best ways to increase that or to either take tryptophan empty stomach
were to eat a high glycemic high glycemic carbs or to exercise and mices
you know if if not having enough tryptophan entering to the brain can be
a limiting factor for for onset insomnia it just seems logical to me that if you
didn’t get enough tryptophan into the brain to make enough melatonin precursor
to keep synthesizing melatonin through the night for eight hours basically that
it could also be a factor in how long you stay asleep and so I think that you
know and i and i think this is true for some people because I know people that
can’t sleep through the night unless they take ten milligrams of melatonin
before they go to bed right and so clearly there then what makes them fall
asleep if they do wake up and they don’t take the melatonin is eating especially
carbs especially carbs yeah right and so and so that lines up very nicely with
their getting and they’re getting melatonin precursor stored in their
brain but just maybe only four hours worth and then they need to get another
four hour dose of it whereas if they take ten milligrams of melatonin then
they for some reason the absorption from the gut slows a lot we have a higher
dose I guess it must the absorption must be saturated or something because the
curve in the blood like the Hat like the half-life in the blood just gets well I
don’t know if it’s the half-life of the individual molecule but like the if you
take a really large dose of melatonin you can stretch out the peak curve and
how that lasts like across the whole night basically even if it’s not time
release and so yeah I think that I think that winds up there I also think that
there are some people particularly people who do a lot of high-intensity
exercise and don’t eat enough carbo high great who are not repeating their
hepatic glycogen before they go to bed and so your your liver has generally
stored about 90 grams of glycogen – for the purpose of maintaining your blood
sugar between meals the longest time that you ever go without a meal is
overnight and so that’s when your liver has the biggest task ahead of it it has
even more of a task if you’re practicing any kind of time restricted feeding
quite often people are practicing time restricted feeding are also practicing
high-intensity exercise and are also practicing carbohydrate restriction and
so you know you might have a crossfitter to eat 60 grams of carbs a day is
deliberately winding back the length of their evening meal to 4 p.m. and they
don’t know why they’re waking up at 3 a.m. with the heart pounding every day
and I think that’s because they are bearing an adrenaline their cortisol
response irritable and so I think that can be a big issue for people who are
early weakening as well and if you both of those conditions if you’re not eating
enough carbohydrates to keep your liver glycogen full you’re not you’re probably
not getting enough to get tryptophan in your brain and if you’re not getting a
tryptophan in your brain to make melton all know you’re probably not getting the
tryptophan your brain make serotonin either so all of those could could could
kind of feed into the same mechanism that you were describing the
glucocorticoid suppression of serotonin levels so I think that’s a couple more
things that yeah cool thank you for your question anonymous really quickly okay
li li w who had the sports question Li W also asks I’m 42 and I’ve had one ovary
removed my hormones are in the trash my doc has recommended starting
progesterone 100 milligrams we bumped up the estrogen gel to 0.5
milligrams my hot flashes during the day have improved but I’m sleeping terribly
I waked up between 2 to 3 a.m. every night sometimes I still sweat at night
should I consider increasing either hormone what was the route of
progesterone was it topical or oral I’m sure it’s oral yeah so well the good
thing is we just answered that entire question about sleep
so take apply that but on top of it it often means you may actually need more
progesterone like I was saying the very beginning of this that progesterone
actually turns into that neuro steroid a low pregnenolone which can cross the
blood-brain barrier and bind itself to gaba and affect sleep it’s very calming
you know obviously relaxing it’s it’s gaba so often times a hundred milligrams
now here’s the here’s the kicker – it depends what your hundred milligram oral
tempo bless you capsule is so pro metrium which is the prescription
medication if you read the package insert pro metrium actually says in
there that has it has about a 10% ten to twenty percent absorption rate which
means of the hundred milligrams and depending on how well your microbiome
and everything your stomach acid is you’re looking at 10 to 20 milligrams of
progesterone out of that pro metrium there’s a lot of binder and filler in
pro metrium there’s peanut oil and premium and so it can it can get in the
way so i do i have found and over the years of practice that if you have
prescription pro metrium you may need to go higher you may need to do the the 200
milligram dose you can also have a compounded though and then that way they
don’t have all the extra binders and like crazy crap binders and fillers and
the peanut oil they take all that out and they just put you know it’s called
oral micronized progesterone OMP and then you can you can then compound it to
any dose you want so you could do 150 Mike you know milligrams 125 175 200
whatever but usually it’s the progesterone that has the bigger effect
on sleep as compared to estrogen although estrogen is important but I
usually start with progesterone before I raise the estrogen and usually find good
results things that effect sleep – right sorry I don’t mean to cut you off but
you know if you’re like if you’re norepinephrine is going up at night if
your blood sugar issues if your cortisol is going up at night it and
norepinephrine is a big trigger for hot flashes for women especially night
sweats it’s a it’s it’s one of its it’s one of its symptoms
women think it’s night sweats from hormones and really it’s from
norepinephrine so getting stress under control
you know winding down at night those things would if you’re on any kind of
adrenal support nourishing adrenal as opposed to stimulating adrenal can be
really helpful also we adds yes among Pro metrium also
I’m one of those folks who’s working out hard practicing time restricted eating
carbs causes well it’s it can be hormonal just like it can be for women
so I test all the same hormones in men I checked their thyroid with night sweats
I definitely even check same thing core I checked cortisol and I do
norepinephrine markers with night sweats and and this is this is also assuming
that I don’t suspect cancer because night sweats is a it can be a key note
especially in men night sweats can be a key note for certain cancers and so I
want to make sure I’m not suspicious of that but it’s to say for women blood
sugar issues hormone issues cortisol issues and making sure you’re not
sleeping in an extra-hot room which because men can get hot there are night
sweats from being overheated just like women can you know sort of those basic
things – I just got a chilly pad I’ve been thinking about it getting a chili
pad for years yeah and I went to a little conference where the guy who
invented the chili pad was there and he let me borrow
for the night and you’ve bought the chili pad in fact I if I were any of you
I would not buy the chili pad I would pre-order the Euler which is their new
model that’s shipping in June and but I wanted it so badly that I bought the
chili pad with the intention to buy the new model when it when it comes out in
June but in the new model you’re you’re gonna be able to control from the app
like it’s it’s at least hour-by-hour might be minute by minute when you want
the temperature to go up and down and there’s a there’s a warm two-week
function so just gradually increases in warmth by you know leading up to when
you want to wake up which ties in nicely with the data from a few years ago
showing that in hunter-gatherers who sleep outside
they wake up before the sunrise with the with the increase in core temperature
being which is driven by the increase in the ambient temperature as you near
that’s at sunrise that is the key trigger for the waking so that’s a
natural function in it and also there I think there’s a lot of people who who
sleep much better at a temperature that is colder than than the temperature that
they fall asleep at and so you can’t currently you can’t you can’t currently
make the timing function with the current model the chilli pad but with
the one that’s coming out in June you will be able to and you’ll be able to
set it so that it goes to maybe like 65 or whatever feels comfortable to you
while you’re actually you can warm it to 110 so yes so like you could have it you
know if 75 is comfortable to you when you’re falling asleep and you can have
it so that 20 minutes later it goes down to 55 which is not the temperature that
it feels like the room is it’s the temperature the water circulating in it
so I like the ambient temperature like 64 is my best temperature to sleep bad
but I keep the chilly fifty-five visit good diet sort of like
but what I noticed was I will usually have complete insomnia at anything above
72 ish I have great difficulty at 70 and 72 74 is the threshold where I just will
not fall asleep right and I can have my room as hot as 80 and sleep well chili
pad is set at 55 and so I’m really excited about that for the summer
because I think that it’s much less stress on the air quality to not have to
run the air conditioner as much and also on the way my room is set up it’s really
hard to to not to have the a/c on and not having it blow on me while I’m in
bed so I think it’s and yeah I’m just super excited about it and I wrote it
down gotta throw it out there if you’re if you’re gonna bring up the room
temperature for the night sweats absolutely alright thank you anonymous let’s mindy cabrera says dietary
nutritional advice for breast cancer prevention macronutrient ratios micro
nutrient intakes etcetera also any thoughts on risks and benefits of HRT in
perimenopause relative to breast cancer risk my mother died in metastatic
lobular breast cancer but she used premarin according to 23 and you have
the gene associated with lower levels of SHBG so did she
so I think I need to be more cautious with exhaustion Asst estrogen any
thoughts scary what was the first part again is macronutrient ratios and micro
nutrient intakes for breast cancer prevention well that’s probably better
for you when it comes to like nutrient ratios and stuff but I will say working
for an estrogen lab what we’re looking at phase 1 and phase 2 detoxification
and what were what we’re trying to assess with estrogen so when men and
women we make estrogen and then we had we detox or estrogen right and so we go
through phase 1 detoxification and that becomes well it becomes a reactive
oxygen species essentially and we and we quickly neutralize it our
body has these systems in place to protect us but if one of your pathways
for phase one does not get neutralized that it turns tail and it goes down I
call the Nadi pathway technically it’s called the Quin own pathway which starts
with the Q and so to it and then that pathway continues on it can lead to DNA
damage there are these things that are creating a lot of pathways a bad one it
is with Q and so they form addicts and addicts ad D u CT addicts when they’re
unstable they bind to the DNA and a break off and so now your DNA goes oh my
gosh there’s holes in my DNA I have to repair them the more holes you have the
higher chance you get for a mutation now estrogen is not the only thing that can
do this you know environmental toxicity
toxicants you know poly aromatic hydrocarbons other things can form
addicts that cause holes in the DNA so from a nutritional standpoint when we’re
looking at before and after testing you know this is when we we get into things
like your Brassica family your broccoli your kale your cauliflower this is when
we get into things like your broccoli sprouts because those those broccoli
sprouts when you cue them or if you cut them up and let them sit on your cutting
board for a couple minutes you activate two ingredients to become
something called sulforaphane and so for a feign is really important and helpful
it’s stopping your estrogen from going down the naughty
quinton pathway and pushing it back to the beginning again plus it also helps
support your phase 2 detoxification and up regulates that some other super
helpful things besides besides that are foods high in breast Verret role your
your your flavonoids your is the phase 2 for that one methylation yes yep so
phase 2 it comped comt is your it’s your big one there so they then b12 and
actually the two big contract Sammy and magnesium for for comped but
obviously b12 yeah maintaining your Sammy levels gonna be is gonna be driven
by the methyl donors and so for sure oh for sure absolutely fully choline but
whatever you know I mean I’m sure as you get this as everyone goes oh just
methylation it’s MTHFR I have that and like well it’s much bigger it’s much a
little bit bigger than that when it comes – youjin and and well everything
but your comt creation and then what it does for estrogen and so when it comes
to breast cancer I’m trying to get women to go get off the quit on pathway or
repair the Quinn own pathway have proper phase one proper phase two and then
phase three is through the intestines so now I’m looking at you know microbiome
support making sure she’s not constipated making sure you know she’s
got fiber and prebiotics and probiotics and just to get the estrogen from start
to finish and so it doesn’t recirculate and increase increase in that regard and
that’s just focusing on estrogen that is that that obviously there’s a whole lot
when it comes to antioxidant support and and everything else yeah there’s some
data that vitamin D and calcium lower the risk of estrogen responsive breast
cancer but only up to the point of only up to the point of levels that would
help your bone health so basically you don’t want to be deficient in those
nutrients but mega dosing them is not gonna be relevant yeah so I but I think
I think that given the relevance of Ceylon tea I would direct people to the
methylation page that I have at Chris master John PhD comm slash methylation
your I mean maintaining your semi levels is going to be dependent on
the methyl donors filet b12 choline but also magnesium and and ATP so in theory
you could have low ATP levels compromising that that would be that
could be related to low energy intake or could be related to taking something
that lowers ATP like bourbon on that Foreman or could be related to metabolic
problems from insulin or thyroid and the Dutch test has tells you how much your
methylating that he does for estrogen yeah the one thing we look at for
methylation yeah absolutely I’ve been actually referring people to
dr. Peter Atia which I know you’ve been on his podcast he did a different
podcast with some blooming and Carol oh this is embarrassing I even have their
book but it’s a great one on s HRT and they have a book out estrogen matters
and I just got mine from Amazon yesterday so I if you are concerned
about your the pros and cons of HRT especially in reference to breast cancer
I would highly recommend watching blooming and cameras that’s what it is
thank you but read the book estrogen matters listen to the podcast it’s
really helpful they present the data in a very able to easy-to-understand way
you did your viewpoint on estrogen change I was never I was never against estrogen
I was always the one of the doctors trying to say that estrogen should not
be vilified it’s against Goldilocks is very vilified right oh my gosh I mean
just look on social media are entire pages dedicated to you know getting rid
of estrogen blocking estrogen and I can’t I can understand if you have
severe endometriosis if you you know it’s like the estrogen has sort of
wrecked your life I understand but what what what I have been wanting
to do is like well but we need it ladies like we need it it is important for our
brain health a critical to our brain health it can help prevent Alzheimer’s
and dementia it helps it’s critical to our bone development it’s critical for
our skin it’s critical for our immune system and if we just do everything in
our power to suppress it you dig the trade-off is we know I mean but maybe we
have dementia and Alzheimer’s so we don’t we don’t know we don’t care but I
care so I want healthy bones and healthy brain and healthy immune system and all
these things so I’ve always been an advocate for estrogen and there was a
compounding pharmacy a couple years ago where they were presenting some of the
data about estrogen and how it’s been vilified and I was so excited and then
when I heard Peters podcast with them I was even more excited and I have not
read the book I just so it’s it’s sitting right next to my bed
did it change yours change your thoughts I also didn’t read the book I listened
to the podcast yeah I mean well I don’t know I’ve been exposed to a lot of anti
estrogen stuff to my actually my view on estrogen was evolving earlier than I
heard that podcast over the last year actually because I’m reading the book
the female brain which is actually an oldish book but but the I mean it comes
across as estrogen comes across as as very important for like mood and things
like that and that book and so that was part of it I you know I was I had a
friend who and we talked about this a little bit I had a friend who was
struggling with with water retention around her period and I was I was I had
been very exposed to a lot of stuff about progesterone being
good hormone estrogen being the bad hormone oh yeah look at a really good
paper that showed that in women who had water retention symptoms with PMS there
the main difference and their hormones was that they weren’t clearing
progesterone as fast from there ovulation related peak and I was
discussing this with a different friend who had found that she would
consistently get water retention in response to using progesterone creams
and so there were a couple things that were kind of all making me a little more
Pro estrogen than I had been in the past likely help so sing that podcast I’m
still left a little confused though if if estrogen is protective against age
related dementia why does most Alzheimer’s happen in
women like the one the three big risk factors
because we’re like a big reason right that we’ve we are protected up to the
point and then we go through menopause and we’ve lose all that estrogen production of estrogen and a
postmenopausal woman’s production of estrogen I mean it’s really interesting
to look at oh I wonder if I’m I’m so uneducated about this that I don’t know
if my speculation does more good than harm but I wonder if it’s related to the
change in hormones because so the female brain talks a lot about estrogens
influence on just modifying the synaptic density of various parts of the brain
and and and that changing in after menopause but I you know I was like
maybe men are protected because they don’t they aren’t placed with the demand
of completely rewiring their brain after they’ve set it up for 50 years right
right because men go through puberty and while there are changes and declines
women go through puberty and then you know often there’s pregnancies so it’s
all these spikes and then we go through reverse puberty when we go through
perimenopause into menopause and cognitive symptoms are so big so common
from my parent menopausal women who say I used to remember everything and I now
I can remember anything I have to write lists I feel like I have dementia I have
incredible brain fog I read something and I can’t remember it I can’t listen
to podcasts anymore because I don’t remember what they’re saying or I can’t
really comprehend it I get this all the time from women is they hit their 40s
and into their 50s as their estrogen is going up and down but eventually of
course declines with menopause so and it’s usually it’s it’s not often at
least with my page population a gradual thing it’s not like
for the last you know 15 years you know women will say I’m having to write lists
more and more it’s usually what the heck from my 45th birthday I can’t sleep and
I can’t remember anything I’m like and I gained 15 pounds unlike whoever designed
menopause can suck it it’s so not fair and you know if um in biology
biologically we live a really long time and we weren’t designed to sew women we
had all this estrogen up to a point and and and then we don’t and then we go
into menopause and we have very little up levels very low levels in fact a
man’s estrogen and a woman a postmenopausal women estrogen are about
on par if you look at the reference ranges but he doesn’t go through all the
like crew up-down and stuff and he doesn’t have high levels you know
through a lot of his cycle and he doesn’t get pregnant and so he doesn’t
have all this like excessive normal estrogen stuff thrown his way and thrown
his brains way and then it all gets taken away I mean it’s like sorry we
have 20 minutes left so let’s cut off new questions and then we’ll try to here
so Jennifer Dunlop says getting in late maybe past the time for questions I was
wondering if there are well here you go Jennifer I getting in I was wondering if
there are hormonal phenotypes that would predict whether a woman will have a
cycle without ovulating or simply lose her cycle altogether than under stress
does it relate to body fat so why would a woman have no cycle why wouldn’t have
an ambulatory cycle so remember cortisol is very very very
potent in the brain and so if the body perceives itself is under stress whether
it’s physical mental emotional environmental it doesn’t matter then
reproduction is not its primary focus anymore
is and I heard this I had been thinking this for a long time I didn’t know how
to eloquently say it and then dr. Felice Kirsch set it on stage one day she said
ladies whether you want to or not like I’m sorry but you were put here to
reproduce biology is what you do knob viously not all women do and a lot of
women in fact are trying to avoid it but that’s what the body is setup for so
when you were under a lot of stress and under body fat under body weight falls
in that category then you your brain says this is a stressor this is not a
good time to get pregnant I’m going to take away her ovulation and or I’m going
to make her cycle late and or I’m gonna take her cycle away completely
altogether and so we hear that a lot with women who have gone through a lot
of stress job change divorce death sometimes it can even be like just
flying time zone changes can be a huge one for changing your cycle but
definitely when you’re under body weight you don’t make the hormone leptin like
you should and leptin is a big hormone for letting the brain know she’s of a
normal weight she can carry a baby safely and how in a healthy manner so go
ahead and make her late so if you were underweight then oftentimes the body
says nope not healthy not strong enough not evil enough let’s protect her take
away ovulation and or take away the cycle completely and then when the body
sack comes back up you see this all the time in like gymnasts or my CrossFit
earners you stop CrossFit or my chronic marathon runners you know they’ll stop
it and the stress goes down the way it goes up to a more perceived healthy
weight by the brain and then they can be late and have a period regardless of
having a baby as your end goal it doesn’t matter but that’s how the brain
works yeah my my model for understanding this is is pretty similar so I feel like
fertility is largely regulated by the question of can I afford energetically
to invest in the you know 50,000 calories and making a baby the
commitment of or 2,000 calories a day in lactation and
and then and then on the long-term scale you know we invest a lot in the success
we’re not ecoli we don’t just like make a billion babies and see which one
survives the make of huge energetic investment collectively in children and
so if your stress hormones are high that’s saying well whatever we do have
for energy we might have these more important things that are coming first
that we have to deal with before we can make that investment we don’t have
enough energy then it says the same thing on the opposite side of that
equation that we don’t have enough energy to deal with whatever we might
face right now or in the long term and I think I’ve seen some I seen a couple
papers connecting in ovulate and all the Latorre cycles to hypothyroidism and so
I think that you know stress hormones are sort of on one side of this equation
and you mentioned leptin I would also put insulin and thyroid hormone on the
other side the the side of saying we have enough energy stress hormones on
the side of saying we don’t have enough energy maybe not because of an energetic
deficit but simply because they’re signaling us you know a stressful
situation that demands energy and and I think that body fat so being underweight
is a huge if you look at fertility rates there’s some there’s some observational
data where they just look at under the BMI of male and female partners and
basically like to underweight partners are going to be very infertile but then
as you cross a certain BMI threshold you start to see infertility happen again
and I think that’s largely because of a resistance to insulin and leptin on you
know the energy is there but now you’re defectives you’re not perceiving it
properly so yeah similar thoughts on that so Jennifer
adds it seems that I simply do not ovulate under stress but others have a
delayed ovulation and a longer cycle it’s probably just a variation in the
same response do you think yeah I think so yeah
okay thank you Jennifer for your question I need a Morgan says what can
be done to reverse hypothyroidism other than taking thyroid medicine I’ve been
taking desiccated thyroid nature–the royde and one drop of lugol’s iodine per
day my doctor is that a hair test shows iodine of 1.0 however drop of iodine a
my skin takes a long time to absorb I’ll throw in a couple things so if you just
look at the nutrients needed to make thyroid hormone you’re looking at enough
protein in addition to enough iodine but then also the production of thyroid
hormone is a very very dirty process that requires an enormous amount of
antioxidant support and so selenium is very important but also you know if
you’re looking at antioxidant protection you’re looking and not just things that
we think of as dietary antioxidants but you’re looking at protein zinc iron
copper manganese in addition to selenium you’re looking at vitamin C vitamin E
and a whole bunch of a Pandora’s box that you’re opening up so I think that
probably the things that stand out the most of protein iodine and selenium but
really you have a pretty big network of of supportive nutrients in the
background of course everything I just said assumes that you’re missing
something that you need to make thyroid hormone which is not necessarily the
case but um but I covered part of it do you wanna make sure you understand the
difference between are you like you’ve cellular for hypothyroidism so so many
things can get in the way of converting your t4 into your t3 high estrogen
collectin highest LAN high cortisol low progesterone low DHEA have any these
things you may be deemed hypothyroid but believes
these peripheral factors play into it as well okay Thank You Anita oh let’s see
anonymous says no this is a lot of things – do you have any experience with
iodine restriction for treating Hashimoto’s Carrie do you have any
thoughts on them I don’t instruction for Hashimoto’s tell you I
well I don’t have experience with it but I’ll say that I read about this in two
TESE crossings look why do I still have thyroid symptoms when all my lab tests
are normal and I looked at the study study sites and I didn’t think they were
very convincing so there is an argument out there that basically the argument is
that the Hashimoto’s is driven by oxidative stress and driving
inflammation that is a result of not being able to protect the thyroid under
the conditions that make thyroid hormone and so if you put more iodine in there
you’re going to increase thyroid hormone production you’re gonna increase all of
the damaging things that you’re not that you don’t have adequate protection
against and there was a back in the day quite a while ago there was a very
extensive back and forth debate on the perfect health diet website between a
few people on this and I agree with the conclusions that they came to which is
that you under those conditions you definitely want to make sure that you’re
not missing key things that are needed to protect the thyroid but as long as
you’re adequate in those and you know chief among them would be selenium but I
have to add here that I really don’t think anyone should supplement with more
than 100 micrograms of selenium if they’re not measuring their plasma
selenium because you basically have a 50/50 chance of having too much or too
little selenium because the soil distribution is completely random and
and plants do not regulate how much selenium they take up which is which is
diff in principle than every other mineral
like for example if you have a place where the soil has toxic levels of
copper in it it’s gonna increase on average the food copper accumulation by
25 percent because because the plants control their copper intake or uptake
homeostatic me where as selenium they don’t and if you have three times the
level of selenium in the soil you have three times a level selenium in the
plants and and so I don’t think it’s wise for people to just throw 200
micrograms a day of selenium and because they have Hashimoto’s but I I do think
it makes sense to say before I’m gonna supplement with iodine I’m gonna make
sure that I have selenium and the other things in place that I need to protect
my thyroid gland during the process of making thyroid hormone and so but I
think that’s the limit to iodine restriction I don’t think I don’t think
I don’t think it makes sense to treat Hashimoto’s by just completely avoiding
iodine because at some point down the line you’re not gonna whine you’re not
gonna have any favorite hormone if you don’t have any iodine just my thought on
that okay what are the implications for hormonal
balance of following a low carb or ketogenic diet are there concerns to
watch for I’ll throw a couple things out so so first of all if you don’t have
enough carbohydrate to feed your body’s demand for it so even on a ketogenic
diet your brains consumption of glucose goes down 75% but your brain consumes
120 grams of glucose a day when you’re not on the ketogenic diet and so your
your your total demand for glucose is at maximum going down and what I mean the
maximum decrease in your need for carbohydrate would be that you could go
down to maybe 45 grams a day if you’re on a if you’re very keto adapted and
that is I don’t mean and so I’m that referring to the amount of carbohydrate
you need to burn for energy so you can make that carbohydrate through
gluconeogenesis but one of the one of the the key regulators of
gluconeogenesis is cortisol and if if cortisol doesn’t normalize your blood
glucose levels you can also get adrenaline pumping in so you can you can
throw things off that way the other thing is that you won’t find this in any
textbook on hormones but insulin insulin acts on the thyroid gland to mimic about
half of what TSH does on the molecular level and so insulin is like if you look
at like how much TSH do you need to make the amount of thyroid hormone that you
need it’s contextual among your it against your insulin level because if
you take out the insulin then your you basically need more TSH to make the same
amount of thyroid hormone and if you’re not ramping up the TSH you will probably
have a decline in thyroid hormone and in fact if you look at t3 levels on low
carbohydrate diets they tend to go down and some look carbohydrate diet
advocates will actually like there are some people that think low t3 is good
for your lifespan whose the I think Ron Rosedale was making this argument that
that you want to be on a low carbohydrate diet so that you will lower
your ki 3 so that you will live longer so there’s that and then also elevated
free fatty acids is going that’s one of the factor and you were talking about
peripheral thyroid hormone metabolism so one of the factors that determines the
actual transport of thyroid hormone into the cell and binding to the nuclear
receptor to affect gene expression is the free fatty acid level so I think
declines in and thyroid hormone regulates sex or
production and other things so I think that you have the potential for a
decrease in thyroid hormone and sex hormones and an increase in cortisol and
not saying that happens in everyone but it’s just one of the things that could
happen and I remember talk I originally was very interested in this because I
was talking to someone who was a type 1 diabetic and they were managing your
type 1 diabetes by basically eating zero carb but their testosterone thyroid
hormone levels were low and their question was clearly there’s a
cause-and-effect relationship there but is it better than carbohydrate intake
insulin or is it better to live with low testosterone levels and so that that’s
though those are my thoughts do you have anything you want to add to that the
number of people that are on a keto type diet and their hormones are a mess he’s
often I have a lot of doctors a lot of practitioners we’re trying something
like that they call me and they’re like I sell terrible I feel like everything’s
a mess they’re also a mess people are doing great to have no issue but doing
keto is testing and feel really good patient population I’m seeing are you’re
calling me because something’s wrong yeah yeah problem as a follow-up to what I was just saying
about the insulin and this this was actually posting a while ago not in
reference to be saying the same thing in a different context Chris has talked
before about the importance of insulin signaling the thyroid function is there
an optimum number of meals per day for optimizing thyroid function ie number of
insulin spikes today I don’t think so the the main influences on thyroid
function are going to be the total area under the curve of insulin you know
assuming that you’re controlling for the level of insulin sensitivity on the
thyroid gland and then also the info I guess if I had to throw out a wild guess
it the free fatty acid concentration is probably mostly relevant when the when
the free fatty acid levels are really high and so it’s probably not the case
that you want to just like it’s probably I don’t know I you’re if you go a long
time without eating food or you go or you eat like very high fat very low carb
acutely that in that context is probably when the free fatty acid levels are
getting the highest if you’re spreading your meals out more you’re probably
never going to have as big of a peak or you’re spreading your carbohydrate out
more you’re probably not gonna have as you might have slightly elevated free
fatty acids and never actually cross the threshold for that to matter but I still
think the dominant things on for insulin on the fire is most looking just gonna
be a average cumulative thing so I don’t think that the number of spikes is gonna
drive that it’s my thought I like it okay
I’m on bio tour moans B IOT I’m not sure if that’s misspelled er that’s okay my
bio T hormones think testosterone is causing acne in male pattern baldness
I’ve been remiss dosterone at pellet insertions DHT tests showed low levels
am i correct correct to keep producing testosterone is it possible to avoid
male pattern baldness I’m 69 and female she thinks testosterone is causing acne
and male pattern baldness she has been reducing testosterone at
pelleted insertions DHT is low am I correct to keep reducing testosterone
and is it possible to avoid male pattern baldness so if you’re just doing
that’s usually what everyone tests your own or into Ostrom intestine you’re
interesting and so a DHT may be low in women but I’ll see the aired rostrum be
really elevated which is more common in women I see yes you can decrease
testosterone but you need to get yourself sort of off to find all the
pathway and so that’s when you’re looking at one lifestyle so decreasing
stress look at your insulin but then supplemental this is what you’re looking
at the things like saw palmetto stinging nettle great pygeum africanum egcg from
green tea reishi mushrooms zinc those things help reduce the 5-alpha effect to
reduce the male pattern baldness effect so that’s usually what I see it’s not
you can’t reduce the testosterone but really it’s the pathway it’s going down
you’re probably just missing the metabolite that’s causing the problem
alright we are out of time thank you so much dr. kerry jones for showing up
really fun and yeah there’s a cancel questions that we didn’t get to but for
the ones that are most hormone-related Carrie where where should people get in
touch with you if if they want to ask you a question at some point dr dot
carrie jones and that’s where i have tons of educational posts and respond to
stuff cool all right thank you so much Carrie this is really fun thank you
everyone who showed up and have a wonderful evening this episode is
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body than simply your adrenals in his epic work nutrition and physical
degeneration Weston Price recorded a story of natives who cured blindness
using eyeballs which are very rich in vitamin A but now that we understand
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liver good for your eyes our ancestors made liberal use of organ meats both to
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animals in the wild do the same Weston Price had also recorded a story of how
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observed what the Lions did when they killed zebras in the wild what they did
was they went straight for the organs and bone marrow leaving the muscle meat
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this ask us anything about hormones and found it useful you can find more of dr.
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Comments

  1. What about issues breaking down / processing progesterone in those with severe progesterone intolerant individuals – premenstrual dysphoric disorder individuals?

  2. I have one question for you. Maybe you could do video of this one…

    So, how should I use niacin supplements on keto? What is the timing if there is a window where body stops using fats for two hours? I've noticed my energy level drops for a while after takin NR. It really goes up for maybe one hour and drops for on hour and I feel tired.Then energy levels come back after that and every day feels really good. With fasting, it's like euforic. But every time comes this little bump on the road. So should I take it or not and when with keto..?

  3. So grateful for these videos, thank you for sharing your depth of knowledge. Interested peaked for all additional educational summits or series.

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