How Does Adderall™ Work?

It can make you happy, suppress your appetite, reduce fatigue, increase your attention span, and it’s used to treat narcolepsy, depression and ADHD. What magical substance does all of this? Adderall. [Reactions intro] Over 25 million people worldwide use amphetamine, which is the active ingredient in Adderall. Amphetamine has actually been around since the 1800s, and has a pretty neat history. First synthesized in 1887 by Romanian chemist Lazar Edeleanu, amphetamine appeared on the market in 1933 under the name
“Benzedrine,” or Bennies for short. In 1943, the US army began issuing “pep pills” to fight battle fatigue and boost morale. These pep-pills were pure amphetamine,
which is a stimulant. By the end of World War II,
American and British troops had shipped an estimated 150 million of these pills. Japanese and German troops also used these “pep-pills” and Hitler would get daily injections of amphetamine. American troops continued using amphetamine well into the Korean and Vietnam wars, but stopped once the drug was no longer sold over the counter in 1956. Because, you know, unrestricted access to pure amphetamine is probably not a good idea. Today amphetamine is used in LOW doses primarily to treat… Wait. What? Oh. Right. Used to treat ADHD. The majority of ADHD drugs stimulate
the central nervous system. You’d think it wouldn’t make sense to treat hyperactivity and lack of focus by adding stimulation, but we’ll let neuroscience expert Doctor Ryan Davison explain: “People with ADHD tend to have lower levels of dopamine, a key chemical in the brain’s reward center. This lack of dopamine means people with ADHD are constantly seeking stimulation. Amphetamine stimulates the release of dopamine and other neurotransmitters in the brain so those minor distractions don’t cause you to lose focus.” Nerve cells and neurotransmitters act like they’re at a middle school dance. Neurotransmitters like dopamine are on one side of the gym, and receptor cells sit on the other. Amphetamine starts the party by pushing dopamine out onto the “dance floor,” where they then partner up with the receptors. Amphetamine also keeps dopamine on the dance floor, leaving more for the receptors to catch. So before we go, here’s DOCTOR DAVISON with another fun fact that shows why little tweaks in structure can make for BIG changes. “Here’s what a molecule of amphetamine looks like. This little guy is a group of a carbon and three hydrogen atoms, also called a methyl group. If you add one more methyl group onto the end of an amphetamine molecule, it turns into its much more dangerous cousin, methamphetamine. Those four little atoms can turn you from a studious citizen… into a total tweaker.” So while you’re still focused, don’t forget to like share and subscribe. And if you enjoyed this, be sure to check out some of our other videos on how caffeine works and learn all about marijuana. Have an idea or suggestion for us? Let us know in the comments or hit us up on Facebook or Twitter. And hey, thanks for watching.

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  1. I have ADHD and ADD. I take concerta,vitamin b5,vitamin b12,vitamin b6 and Magnesuim. But I still nd I need have trouble focuing in my first two periods in my high schol courses but in period 3 and 4 thats when I can focus the most but thats not how my life used to be. I think that I need a higher dose of concerta like the 54 and adderall.

  2. I am an avid #MentalHealthAwareness advocate and performer, and I love this so much. I travel the country trying to bring that awareness on stages, in classrooms, hospitals, and on my YouTube channel, so I get excited when I see other advocates. 💙❤

  3. One of the most interesting channels I subscribe to. YouTube red subscriber for 3 years now. Subscribed. Thanks for your work!

  4. About twice as many children gets diagnosed with adhd, than children who actually have adhd. When you add into the calculation that many adhd children goes undiagnosed, you quickly realise this drug is being given to too many children

    This is part of why this whole "adhd isn't real" myth has occurred. Misdiagnosis is never a good thing, people lose trust in the health authorities.

    Then often it's given in too high dosages as well. So even when it is prescribed to actual adhd kids, it's often not prescribed correctly.

    Behind this all we have the drug industry. When you look at countries where the drug industry doesn't have the same power over health services as they do in the US, you find that they usually don't use Adderall. Their go-to drug is Ritalin, which technically functions the same way but has slightly less risk of addiction and side-effects.

    In the end, people who actually has adhd have a less likelihood of developing drug addiction if they get treated with amphetamine. They have less likelihood of dying in accidents. They function better in society. So there are positive effects of adhd medication. But the way it's being done in America right now is just abuse, big pharma is pushing this drug on kids who don't really have adhd.

  5. The truth is the majority of people that feel they need some kind of dopaminergic modification, whatever from, is actually from the constant instant reward that we now have.
    We've literally burned out our receptors with puppies, chocolate, ANY kind of screen (phone, TV, Comp etc). Our foods all have intentionally addictive chemicals added to them or designed to increase dependency due to sugars, fats and salts. (I.E constant pleasure seeking)
    We live relatively pain free lives. Typically the modern person endures no external hardship or suffering. Famine, imminently dangerous disease.
    Everyone takes pain medication for everything and so on and so forth.
    When this happens it raises the baseline which makes "mundane" tasks seem uninteresting, boring and of no value to our brains.

    This is NOT to say however, there isn't a real genetic components (IE inherited and not developed) ADD problem, which of course gets passed on generation after generation increasing in the population.

  6. Very unprofessional of the Dr. to speak of Methamphetamine like that. Methamphetamine being one methyl group away from Amphetamine is not a negative, which is why it is still prescribed to this day (Desoxyn). It is mainly used for its longer duration then that of Dextroamphetamine/amphetamine (adderall), the real danger of Meth is the impurities found in its street form (crystal meth)

  7. The problem is the neglect of medications needed to help with the withdrawal. I find it astonishing that amphetamine/stimulant addiction has no well know withdrawl drug. Opiate users have many options with methadone, Suboxone, naltrexone,etc.. alcohol/benzodiazepine users have gabapentin yet nothing for Adderall other than “therapy” when doctors hand it out like candy. There is a withdrawal there is body pain there is mental side effects, etc. and your dopamine system is screwed for a very long time. You can’t just let someone go without helping with medications and only using therapy. There are ways to help upregulate dopamine and not just stick this out.recently I read some pieces of Dr. Edward Fruitman who seems to be extremely knowledgeable with the importance of medications needed to ease the withdrawal. He also mentions testing as many people like myself ultra metabolizers. He brought up Topamax(Topiramate) in several studies.they used it in cocaine and methamphetamine addicts during tapering off. Not only did it help reduce tolerance but it actually increased the positives instead of attenuating them like most tolerance/tapering drugs do. Just because the rest of the seizure is rare from amphetamine withdrawl doesn’t mean you can negate all the other side effects that come with it which can be very life-threatening and ruin someone’ entire world.

  8. Adderall destroyed my beautiful wife….that stupid drug got her what she always wanted…..a college degree….but, it eventually led her to psychosis…and now up till this day (8 years later) she has been taking all kinds of other mind altering drugs prescribed by her psychiatrist…she never really got stabilized like she once was… shes homeless ….about to be divorced and lose custody of our children….GOD PLEASE HELP HER!!!……so with that being said…..FUCK YOU BIG PHARMA…..YOU FAGS SEE NOTHING BUT $$$$…..ROT AND BURN IN HELL BIG PHARMA FOR RUINING OUR LIVES

  9. People can hate on it but theres some of us who truly rely on this. Ive not had insurance so I lost my RX and have been several years without it. Its god awful. I stay dealing with bipolar depression and loose everything and stay feeling down and lost. But when a friend lends me a few aderal it literally makes me want to cry because i finally know im going to atleast have a couple days of being the better version of me. Hoping soon I can get on some insurance even though its going to cost 400$ a month. I need my sanity back and to feel normal again.

  10. Guys I have to take addarol and it's not fun at all. It's honorable at any dose. Idk why people can't embrace kids and adults with ADHD.

  11. I have ADHD and take Concerta. When it first came out, my doctor didn’t know much about it so he started me off with 84mg for the first month. I asked him to lower the dosage since I needed the medicine to help focus, not to get addicted to it.
    I now take a total of 72mg per day which is the right amount for me. I’m still hyper and don’t need much sleep (4 hours a night, sometimes less) but I can focus now and keep a straight thought in my mind and I’m finishing what I started instead of living with chaos and frustration and unfinished projects all over the place.
    I still get stomach cramps from the pills but it only lasts for a little while and I’m not constantly depressed or frustrated.
    My kids have ADD and choose not to take medication for it, which is fine with me since they are doing a lot better than I did without medication.

  12. You know I took this medication when I was going to 6 grade and it been 5 years since I had that focus. But now I'm dealing with the side affects of lack of focus, high blood pressure, vision changes( for the past 3 years my vision had gotten worser and worser than my own mother's) and drowsiness after the pill wears off. The doctor understand that I had this blood pressure issue but didn't precribed me any meds to control it or even discontinued it.

  13. My ADHD was killing me until I got my medication and now I’m doing great in school, I can finally pay attention

  14. Who else peeped the mistake on the drawing of the methamphetamine molecule? (2 bonds on hydrogen instead of nitrogen) LOL! like if you did ; )

  15. Make the world fun with a bunch hyped up little hitler nazi's. What's that driver coming toward you on. How about that pharma induced school shooter?

  16. Adderall is an interesting drug. It helps people but can also really ruin people. Sometimes it causes depression and I usually forget to eat. It’s a horrible life living with ADHD

  17. Guys you should not rely on a drugs too much to improve you quality of life…Aderrall is nothing but amphetamine, it will get you used to taking drugs everyday and may lead to methuse or whatever. The schoolsystem knows only of one way to teach things, but there are others pedagogic methods. Increasing the fun and interesting in learning! You really don't fucking need to drug kids…
    Try find a job or formation that wakes your interest or get yourself together to do what needs to be done…If drugs is your only motivation it can't be any good.

  18. Stupid and needlessly cartoonish video.
    Children will not be drawn to the misleading information you're trying to spread just because you added shitty animation and some retarded music to the background of the video. These retarded boomer analogies, from someone who is clearly at least 10 times older than the audience they're trying to reach, only makes this video noisy and embarrassingly cringy.

    It's no wonder the education system is on it's knees. When you have this type of out of touch boomer in charge of what and how young people are supposed to learn it's no wonder they despise school and straight out hate education.

  19. This video should be more scientific from a psychological perspective since you’re trying to inform your viewers about it’s mind altering affects. All videos regarding scientific research about drugs should always clearly state that their information from their studies are always a subjective interpretation of how a group of participants who where examined from their personal perspective. You can not completely control all controlled variables in a scientific study on someone’s conscious experience on a drug. Therefore any conclusions made at the end of a study gathered from a group of individual cannot be replicated precisely if the testable procedure was retested by other scientists across the globe. Their participants could have a different level of IQ and other habitual daily life activities that have shaped their personalities from the moment of birth. Hence everybody has and makes different life decisions based upon their own motivations. For instance, some studies have reported that adderall and other amphetamine only make you feel smarter. That claim made in numerous studies is highly vague, and highly debatable on the basis if an individual already possess a high IQ and takes the same substance could potentially use and access more of his or her intelligence than someone of a lower IQ.Reports coming from Harvard universities present information about how students use adderall and other amphetamines to progress effectively and efficiently through their academic degrees. Unfortunately I cannot paste my secondary sources from my college’s database since this is only a YouTube comment, but if you surely do your research you can uncover a whole new perspective on the effects of drugs on the psyche. Just think logically here. There’s some who drink or smoke until they’re 90 years of age and still live longer than healthy individuals. Individuals like theses represent as Outliers in statistical data in a case study which also can make the end results more subjective than fact. The scientific method has not reached a point to where it can claim conclusive results for everyone. Hence all results from research regarding drugs should be claimed as a subjective claim to the original hypothesis and made clear that everyone can experience mind altering substances differently.

  20. Don't let this distract you from the fact that long term drug use, even these ones, will fuck with your baseline hormone levels (dopamine, noradrenaline, serotonin etc.) and such and are likely to cause receptor downregulation in the long term, which results in you having to up the dosage and becoming dependent on it and feeling like shit when coming off it for what could be quite a while. Also sides effects of these kind of drugs can be stuff like pyschosis and depression in the long term; so while you're getting more dependent on them you're also likely to experience those things at some point, so good luck with that too. these drugs are neurotoxic (damage neurons) and will damage your brain aswell with that said, so there's another plus, yay. I remember when i got off them (after 4 year of use for my ADD) i experienced mild to moderate depression, anxiety, panic attacks, mild paranoia at times and
    dysphoria for about a year. This shit fucks your brain in the long term and it's not worth it in the long term. Perhaps very very occassionally for about one day in a row, although i wouldn't personally recommend that either. There's a lot more to be said about it but i want to keep it somewhat short.

    Find other ways to treat your ADHD/ADD, as someone who has it i can confidently say that is possible. Think about high protein, very healthy, low carbs, no sugar (aside from fruits and stuff, just no artificial added sugar) diet, exercise a lot (personally prefer anaerobic as it feels more stimulating to me), meditation, very good regular high quality sleep, nootropics like omega-3 fatty acids (people with ADHD/ADD tend to break this down at a faster rate therefore highly recommend to supplement), other supplements in vitamins in minerals commonly lacking in people with ADHD/ADD; etc. etc.

    Drugs are not a proper sustainable way to treat your problems.

  21. I work in a pharmacy at Los Cabos,México and there's a lot of people from USA who looove to buy me Adderall and Ritalin 🤣 And they never forget Xanax Haha Haha

  22. People w out ADHD don't understand. But it calms me down LIKE valium. Ya I know. That why people with out no understand.

  23. Claiming that methamphetamine turns "a studious citizen into a total tweaker" is a greatly inaccurate statement as it is by nature pharmacological determinism.


  25. H2O is only one hydrogen molecule away from H2O2. One of them is essential to our survival, the other is poison to us. Just because it has a similar structure doesn’t mean it’s comparable.

  26. Interesting how nobody asks him/herself why today we have an epidemic of kids with ADHD, while 40-50 years ago only a small minority of kids showed the same behaviors. And no, it is not about better diagnostics, today kids' brains are getting wired and developed differently. The video is extremely irresponsible for portraying as a magic solution something that is in fact an extremely powerful and destructive drug for adolescents whose brains are not even entirely formed. First of all, there is only a minority of the people who are prescribed these drugs who really have obvious reasons to take them. Second, there are methods that help rewire the brain and increase the ability to concentrate and focus attention that do not involve the use of any drug, like meditation, yoga, martial arts. Let's face it, giving amphetamines to an early teen on a daily basis will most likely cause serious side effects both physiologically than psychologically. I cannot even bare the idea of submitting my brain to such a regime on a daily basis. Aldous Huxley had seen this already more than a half a century ago, he clearly understood how drugs would eventually be used on people starting at a very young age to shape their minds to obtain their support and willingness to be part of a society in which they are nothing more than modern slaves controlled from above. Start looking beyond the mainstream crap information provided by channels like this one

  27. My 5th grade teacher told my mom to put me on this shit. No adds and I’m still living the adhd life and kicking it my guy.

  28. i walways thought ritalin and adderall were to CALM you down and that if anything they were a depressant because you cant focus and your brain would if anything need less stimulation. its sooo weird that maybe adderall would actually HELP ME because ALL my life in school and at work i couldnt focus i would not want to be there because i was lazy but i had anxiety and low energy and it would really make me unable to learn at school or even understand directions from your boss. after my boss would say something because i have anxiety and depression and i beleive add i wouldnt grasp or sink in what i was told. i just thought maybe it was depression or anxiety alone or back pain but now that i think of it its probably my ADD and adderall would probably help me be productive because literally for a decade now ive been struggling with having a purpose in life! i literally just feel like i have zero energy and mental exhuastion

  29. Norco for 10 yrs..stop on Adderall…46 yr old finally found out I have ADHD..60 mg on my first's almost think I stick with 10mg twice a day and see how that goes..what I got to lose

  30. Ask the biggest user of Adderall how it works—Trumpfuck the snorting 400 Pound lying corrupt perverted orange piece of shit !!!

  31. Idk about this one chiefs, i might get diagnosed with ADHD soon but if i do should i take this to treat it? My therapist told me the reason he thinks i have it is because my constant fidgeting, my attention span is very low, easily distracted, and constantly bored or get bored quickly anyone who has this problem and takes adderal pls help me make decisions

  32. For those who have never tried it, avoid the IR Adderall's and get the XR Version. The IR pills are like rocket ships, they shoot you up really high really fast similar to Meth. The IR Version of Adderall is more abuse-able and has more side effects including feeling totally tweaked out. The XR Version is much more subtle, better for those who use Adderall for productivity/focus/motivation. The IR Version is really only good for recreational use, or for those who may only need a 4 hour Dose worth. An Adderall XR lasts about 12 hours, so you take it in the morning and are good all day. Once your body becomes accustomed to it, which happens fast, you'll have no trouble sleeping. At first the XR may effect sleep. #My2Cents

  33. So last week i got faded off adderall and i felt like a whole different person i was i zombie and im in middle school and dont have adhd so i my body felt light and shitt i couldnt really feel pain either i was sleepy asf

  34. I take aderall or vyvanse once a week recreationally so I don’t develop an actual dependency, and it does wonders for productivity. I end up completing homework and projects a week ahead, and clean my room multiple times. It is also great if you play guitar because you can end up playing with no pain for hours on end. It is amazing and I have energy for hours, and the come-down doesn’t affect me negatively at all, it is the cleanest “high” you can get if you want to be crack-head level productive.

  35. I wish I could go back to the day i first tryed adderall. It ruined my life. Whoever is reading this if you ever get offered adderall or have a chance to try some DONT DO IT! Its just not worth it!!

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